- Analysis of personalized genetic testing for HLA-Cw6 to predict secukinumab success just accepted in JEADV (20 Dec 2017)
- CTI Grant accepted for new skin measurement device (Opus Neoi, with M. Bonmarin, Dec 2017)
- Prof. Navarini and Dr. Glatz organized the academic meeting “Unequal twins – Atopic eczema and Psoriasis” (9 Dec 2017)
- Prof. Navarini to speak at European Academy of Dermatology and Venereology Congress about IL-1 and pustular diseases (15 September 2017)
- Prof. Navarini introduced the Swiss Technology Assessment of Personalized Medicine at the public event of the Swiss Personalized Health Network in Berne (28 August 2017)
- Virtual Derm is out now – our virtual reality game that teaches you to treat psoriasis patients! Available in iOS app store and Android (2nd version 28 August 2017)
- Our analysis of >100 patients Acne excoriée des jeunes filles was just accepted for publication (22 July 2017)
- Swiss Rosacea Guideline accepted for publication in JEADV (10 June 2017)
- SkinApp, our hand eczema detection machine, was just presented for the first time at the international Skin Allergy Meeting 27-29 April in Zurich
- Prof. Navarini spoke about Xerosis – no dry subject! at Basel Allergology Meeting April 6 and SAM 2017.
- “Interruption of Sneddon-Wilkinson’s subcorneal pustulation with infliximab” just accepted for publication! (16 March 2017)
- 200 patients in ERASPEN network (10 February 2017)
- CTLA4 paper awarded the Müller-Dierok Allergy prize (21 January 2016)
- First paper of Swiss Dermatology Network for Targeted Therapies paper just out ! (12 January 2017)
- Review on Allergic Contact Dermatitis just published (10 December 2016)
- White scale sign paper published in JAMA Dermatology (14 December 2016)
- Prof Navarini spoke at Inflammatory Skin Disease Summit in New York on “Investigator-initiated trials” (19 November 2016)
- Fantastic “Future Leaders in Dermatological Research” Meeting in Madrid, Prof Navarini spoke about Investigator Initiated Trials and mentored four young investigators (11 November 2016)
Genetic architecture and resulting phenotype
The Navarini Lab uses a two-pronged approach of analysing genetic and visual data to understand skin conditions.
This page aims to inform and update you about our activities. If you have similar interests, we are always looking for collaborations. Also, the page is a home for the reference assistant that we consider a significant advance for scientific writing - why don't you try it yourself?
Utilizing exome-wide next generation sequencing allows us to detect disease driving genetic alterations. These are then taken forward for functional analysis, which sometimes can lead to novel therapeutic approaches. Our main focus of conditions are the neutrophil-mediated inflammatory diseases (NMID) including pustular psoriasis, pyoderma gangrenosum, Sweet syndrome and others. Other projects include additional immune-mediated conditions.
Our Vision-Team also seeks to extract objective insights out of imaging, which are the dermatologists' most valuable data. We use systematic evaluation of common skin conditions with new visual tools such as dermoscopy as well as machine-learning techniques that enabled us to develop eczema-detecting algorithms.
With these two central themes, we aim towards optimised genotype-phenotype correlations and clinical insights that could be useful for future decision support systems.